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Estimation of In Vivo Half-Life From In Vitro Metabolic Clearance, Protein, and Cell Membrane Affinity Assays

Carla Pou Miralbell1, Sandrine Desrayaud2, Berndt Oberhauser1

  • 1Global Discovery Chemistry, Novartis Biomedical Research, Novartis campus, WSJ-88.10.100, 4056, Basel, Switzerland.

Chemmedchem
|July 19, 2025
PubMed
Abstract

Keywords:
CHI(IAM)half‐lifehuman serum albuminmicrosomal clearancemodels

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