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Updated: Sep 14, 2025

Chromogenic In Situ Hybridization as a Tool for HPV-Related Head and Neck Cancer Diagnosis
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[Cervical cancer: Guidelines for clinical practice].

Xavier Carcopino1, Lobna Ouldamer2, Cyrille Huchon3

  • 1Service de gynécologie obstétrique, CEReSS, Centre d'études et de recherche sur les services de santé et la qualité de vie, hôpital Nord (APHM), Aix-Marseille université, Marseille, France.

Gynecologie, Obstetrique, Fertilite & Senologie
|July 19, 2025
PubMed
Summary

New clinical practice guidelines offer evidence-based recommendations for cervical cancer management, from initial assessment to recurrence treatment. These guidelines aim to standardize care and support healthcare professionals in decision-making.

Keywords:
BrachytherapyCancer du colCervical cancerConcurrent chemoradiotherapyCuriethérapieFollow-upRadio-chimiothérapie concomitanteStadificationStagingSurveillanceTraitementTreatment

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Area of Science:

  • Oncology
  • Gynecologic Oncology
  • Clinical Practice Guidelines

Context:

  • Cervical cancer management requires standardized, evidence-based approaches.
  • Existing practices may vary, necessitating updated clinical guidelines.
  • The 2018 FIGO classification for cervical cancer provides a framework for current management.

Purpose:

  • To establish comprehensive clinical practice guidelines for cervical cancer management.
  • To provide healthcare professionals with evidence-based decision-making tools.
  • To harmonize cervical cancer care in France.

Summary:

  • Developed 158 recommendations for cervical cancer care based on 130 PICO questions and GRADE methodology.
  • Recommendations cover assessment, treatment (surgery, chemoradiotherapy, brachytherapy), follow-up, and recurrence.
  • External validation via Delphi method with 87 experts; evidence quality ranged from high to very low.

Impact:

  • Facilitates standardized management of cervical cancer.
  • Supports healthcare professionals with evidence-based tools for patient care.
  • Aims to improve outcomes for women diagnosed with cervical cancer.