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Nonvitrectomizing vitreous surgery for idiopathic epiretinal membrane
Shuyue Xue1,2,3, Mingming Zhou1,2,3, Dong Chen4
1Eye Institute of Shandong First Medical University, Qingdao Eye Hospital of Shandong First Medical University, 5 Yanerdao Road, Qingdao, 266071, China.
Scientific Reports
|July 19, 2025
Summary
Nonvitrectomizing vitreous surgery (NVS) offers comparable outcomes to pars plana vitrectomy (PPV) for idiopathic epiretinal membrane. NVS provides similar structural improvements and visual acuity, with potentially greater gains at six months.
Area of Science:
- Ophthalmology
- Retinal Surgery
Background:
- Idiopathic epiretinal membrane (iERM) affects vision through macular changes.
- Evaluating surgical techniques for iERM is crucial for visual outcomes.
Purpose of the Study:
- To compare the efficacy of nonvitrectomizing vitreous surgery (NVS) and pars plana vitrectomy (PPV) for iERM.
- To assess structural changes using central macular thickness (CMT) and disorganization of retinal inner layers (DRIL).
Main Methods:
- Retrospective analysis of 117 patients undergoing NVS or PPV.
- Comparison of best-corrected visual acuity (BCVA), CMT, and DRIL points pre- and post-operatively.
Main Results:
- Both NVS and PPV significantly improved BCVA, CMT, and DRIL.
- Postoperative CMT and DRIL were similar between groups.
- BCVA improvement was comparable at 1 month, favoring NVS at 6 months.
Conclusions:
- NVS is a viable alternative to PPV for iERM, offering non-inferior functional and structural results.
- NVS simplifies surgery and preserves vitreous integrity.
- Visual prognosis correlates with baseline DRIL severity, but significant improvement is achievable even in severe cases.

