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Updated: Sep 14, 2025

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
Measuring Success in Renal Denervation: Response Parameters and Predictors of Response
Hyeok-Hee Lee1, Andrew S P Sharp2, Eric A Secemsky3
1Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts; Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea.
Abstract:
Renal denervation has recently emerged as a novel approach to improving blood pressure control, particularly in patients with uncontrolled or resistant hypertension. Although a substantial body of evidence has accumulated regarding the procedure's efficacy and safety, considerable variation exists across studies in the primary measures used to assess treatment response. The degree of response also differs widely among individuals, highlighting the importance of identifying factors associated with enhanced or limited responses to the procedure. In this review, we summarize the currently available evidence on response parameters and predictors of response to renal denervation and offer perspectives for future research.
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