Related Experiment Video

Updated: Sep 14, 2025

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging
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A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging

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PAI-1 is a common driver of aging and diverse diseases

Alireza Khoddam1, Toshio Miyata2, Douglas Vaughan1

  • 1Feinberg Cardiovascular and Renal Research Institute, Feinberg School of Medicine Northwestern University, Chicago, USA.

Biomedical Journal
|July 20, 2025
PubMed

Keywords:
AgingCognitive declineMuscle atrophyPAI-1Senescence

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