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A New Murine Model of Endovascular Aortic Aneurysm Repair
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Positive aortic remodeling elevates the bar for defining endovascular aortic repair success

Valentina Restrepo1, Naiem Nassiri2

  • 1Section of Hematology, Department of Internal Medicine, Yale University, New Haven, CT.

Journal of Vascular Surgery
|July 20, 2025
PubMed
Summary

No abstract available in PubMed .

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Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
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Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
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