Emerging Paradigms in Nanozyme: Strategies in Fabrication, Cancer Targeting, and Biosensing

Area of Science:

• Nanotechnology
• Biomedical Engineering
• Oncology

Background:

• Nanozymes are nanomaterials with enzyme-like catalytic activity.
• They present advantages over natural enzymes, including stability and cost-effectiveness.
• Nanozymes are increasingly explored for medicinal applications, particularly in cancer treatment.

Purpose of the Study:

• To review nanozyme fabrication methods, classification, and properties relevant to cancer therapy.
• To explore therapeutic strategies utilizing nanozymes in oncology.
• To highlight the potential of nanozymes in enhancing nanodynamic therapies for improved cancer treatment.

Main Methods:

• Review of fabrication techniques: sol-gel synthesis, chemical precipitation, hydrothermal methods.
• Classification of nanozymes: natural, synthetic, and hybrid types.
• Exploration of therapeutic applications: targeted drug delivery, photothermal therapy, combination therapies.

Main Results:

• Nanozymes exhibit significant catalytic potential and stability for therapeutic use.
• Their integration into nanodynamic therapies enhances cancer cell apoptosis.
• Diverse nanozyme applications show promise in improving treatment efficacy and minimizing side effects.

Conclusions:

• Nanozymes are promising tools for advancing cancer therapy.
• Their unique properties facilitate targeted cell death and personalized treatment strategies.
• Further research into nanozyme integration can lead to improved patient outcomes in oncology.