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Updated: Sep 14, 2025

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
Neoadjuvant Chemotherapy with Low-Dose Nivolumab Leading to Complete Pathological Response in Non-small Cell Lung
Prasanth Penumadu1, Prasanth Ganesan2, Dhanapathi Halanaik3
1Department of Surgical Oncology, Sri Venkateswara Institute of Cancer Care and Advanced Research, Tirupati, India.
Abstract:
Lung cancer is the second most commonly diagnosed cancer worldwide and the most common cause of mortality. Locally advanced non-small cell carcinoma is treated with multimodality treatment. Neoadjuvant chemotherapy with or without immunotherapy is known to have a maximal response and improves outcomes in stage III lung cancers. Immunotherapy is not affordable in mid and low-socioeconomic-income countries. Here we report a 69-year-old gentleman treated with neoadjuvant low-dose nivolumab (LDNiv) with chemotherapy followed by surgery and it shows a complete pathological response. LDNiv could be an economical option and could be explored in future prospective studies.
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