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Updated: Sep 14, 2025

Murine Model of Allergen Induced Asthma
Published on: May 14, 2012
Aerodigestive evaluation in patients with eosinophilic asthma
Chloe Citron1, Jessica Erkman1, Mikhail Kazachkov1
1Department of Pediatrics, Hassenfeld Children's Hospital, NYU Grossman School of Medicine, NYU Langone Health, New York, USA.
Abstract:
We present two pediatric patients with severe uncontrolled asthma who underwent aerodigestive evaluation revealing eosinophilic asthma and eosinophilic esophageal inflammation. They were subsequently initiated on targeted biological therapy for eosinophilic inflammation with dupilumab resulting in clinical and histological improvement. These cases demonstrate that aerodigestive evaluation is an important clinical tool for characterizing asthma phenotypes and diagnosing comorbidities in children with SUA to optimize their treatment regimens.
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