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  11. Early Postoperative Changes In Corneal Densitometry After Smile With 120-μm And 130-μm Cap Thickness: A Comparative Study

Early postoperative changes in corneal densitometry after SMILE with 120-μm and 130-μm cap thickness: a comparative study

Shirou Wu1,2, Hongying Jin1,2, Ting Wan1,2

  • 1Eye Center, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.

Advances in Ophthalmology Practice and Research
|July 21, 2025

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View abstract on PubMed

Summary
This summary is machine-generated.

Small incision lenticule extraction (SMILE) with 120-μm and 130-μm cap thicknesses showed similar visual outcomes. However, the 120-μm cap thickness resulted in higher early postoperative corneal wavefront aberrations.

Area of Science:

  • Ophthalmology
  • Refractive Surgery
  • Corneal Physiology

Background:

  • Small incision lenticule extraction (SMILE) is a popular refractive surgical procedure.
  • Corneal densitometry (CD) changes after SMILE can impact visual quality.
  • Cap thickness in SMILE may influence early postoperative outcomes.

Purpose of the Study:

  • To compare early postoperative changes in corneal densitometry (CD) after SMILE using 120-μm versus 130-μm cap thicknesses.
  • To evaluate the impact of different SMILE cap thicknesses on visual acuity and refractive outcomes.

Main Methods:

  • A comparative study included 69 eyes (39 patients) undergoing SMILE with 120-μm (n=34) or 130-μm (n=35) cap thicknesses.
  • Corneal densitometry (CD) was assessed in three zones (anterior, central, posterior) at baseline, 1 week, and 1 month postoperatively.
Keywords:
Cap thicknessCorneal densitometrySMILEWavefront aberration

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  • Visual acuity, refraction, and corneal wavefront aberrations were also compared between groups.

    • Main Results:

    • No significant differences in visual acuity or refractive outcomes were observed between the groups at one month.
    • Early postoperative CD increases were noted in anterior and central corneal layers, particularly in the 120-μm group.
    • The 120-μm cap thickness group exhibited significantly higher early postoperative corneal wavefront aberrations compared to the 130-μm group.

    Conclusions:

    • Both 120-μm and 130-μm cap thicknesses are safe and effective for SMILE.
    • Early postoperative CD changes occur primarily in the anterior cornea, with a more pronounced increase in the 120-μm group.
    • A 120-μm cap thickness in SMILE may lead to increased higher-order aberrations compared to a 130-μm cap.