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Updated: Sep 14, 2025

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Intracoronary Acetylcholine Provocation Testing for Assessment of Coronary Vasomotor Disorders
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Coronary Vasospasm Masquerading as Coronary Artery Disease
Muhammad U Rana1, Anuj Garg2, Krishna Prasad Kurpad3
1Internal Medicine, Carle Foundation Hospital, Urbana, USA.
Cureus
|July 21, 2025
Summary
Prinzmetal
Area of Science:
- Cardiology
- Electrophysiology
Background:
- Prinzmetal's angina typically causes chest pain.
- Rarely, it can manifest as ventricular fibrillation or cardiac arrest.
Observation:
- A 78-year-old male experienced recurrent syncope due to ventricular fibrillation.
- Despite coronary angiography and intervention, syncope persisted, linked to polymorphic ventricular fibrillation.
Findings:
- Polymorphic ventricular fibrillation causing syncope was diagnosed.
- Treatment with calcium channel blockers and nitrates resolved symptoms.
Implications:
- This case highlights rare vasospastic angina presentations.
- Effective management of Prinzmetal's angina with medication is demonstrated.
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