Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Spatiotemporal patterns of tuberculosis in urban slums and urban-rural transition zones: evidence from Tétouan, Morocco, 2019-2023.

PLOS global public health·2026

Same author

Acute Negative Pressure Pulmonary Edema Following Upper Gastrointestinal (GI) Endoscopy: A Case Report.

Cureus·2025

Same author

A Longitudinal Prospective Study of Active Tuberculosis Among Patients in Tétouan, Morocco.

Cureus·2025

Same author

Tuberculosis Epidemiology and the Impact of the COVID-19 Pandemic on Tuberculosis Control in Tétouan, Morocco (2015-2022): A Retrospective Descriptive and Analytical Study.

Cureus·2025

Same author

Pulmonary Embolism Originating From a Hepatic Hydatid Cyst: A Case Report.

Cureus·2025

Same author

Reference Values for Spirometry in Moroccan Adults.

Cureus·2024

Search research articles

Related Experiment Video

Updated: Sep 14, 2025

Author Spotlight: Advancing Pathogen Detection and Disease Assessment in Real-Time Using M-ROSE

Author Spotlight: Advancing Pathogen Detection and Disease Assessment in Real-Time Using M-ROSE

Published on: March 1, 2024

Hemoptysis Revealing Microscopic Polyangiitis: A Case Report.

Fatima Zahra Elazizi^1,2, Dalal Zagaouch^1,2, Soumia Fdil^1,2

¹Pulmonology Department, Mohammed VI University Hospital, Tangier, MAR.

|July 21, 2025

Summary

Microscopic polyangiitis (MPA), a rare vasculitis, can present with lung and kidney issues. Early diagnosis and treatment with corticosteroids and cyclophosphamide are crucial for managing this ANCA-associated condition.

Keywords:

alveolar hemorrhage anca-associated vasculitis anti-mpo antibodies cyclophosphamide microscopic polyangiitis pulmonary-renal syndrome

More Related Videos

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats

Published on: March 8, 2019

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots

Published on: October 25, 2024

Related Experiment Videos

Last Updated: Sep 14, 2025

Author Spotlight: Advancing Pathogen Detection and Disease Assessment in Real-Time Using M-ROSE

Author Spotlight: Advancing Pathogen Detection and Disease Assessment in Real-Time Using M-ROSE

Published on: March 1, 2024

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats

Published on: March 8, 2019

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots

Published on: October 25, 2024

Area of Science:

Nephrology
Pulmonology
Rheumatology

Background:

Microscopic polyangiitis (MPA) is a rare small-vessel vasculitis.
It is often associated with anti-neutrophil cytoplasmic antibodies (ANCA), especially anti-myeloperoxidase (MPO).

Observation:

A 63-year-old male smoker with hypothyroidism presented with hemoptysis, dyspnea, and constitutional symptoms.
Imaging showed bilateral lung infiltrates and pulmonary embolism.
Laboratory results revealed anemia, rapidly progressive renal impairment, and high-titer anti-MPO perinuclear anti-neutrophil cytoplasmic antibodies (p-ANCA).

Findings:

The patient's presentation and serology supported a diagnosis of MPA.
Treatment involved high-dose corticosteroids and cyclophosphamide, with dosage adjusted for renal function.

Implications:

MPA should be considered in patients with unexplained pulmonary and renal symptoms.
Constitutional symptoms and positive ANCA serology are key indicators for suspecting MPA.