Related Experiment Video
Updated: Sep 14, 2025

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics
Published on: April 19, 2024
A Comparative Study of Two Inspiratory Pressure Levels for Pressure-Controlled Face-Mask Ventilation in Children
Sateesh Verma1, Tripti Singh1, Rajesh Raman1
1Anesthesiology and Critical Care, King George's Medical University, Lucknow, IND.
Lower inspiratory pressure (12 cm H₂O) during face mask ventilation in children is more effective at preventing gastric insufflation than higher pressure (16 cm H₂O). This finding helps optimize anesthesia induction safety.
Area of Science:
- Anesthesiology
- Pediatric Critical Care
- Medical Devices
Background:
- Inappropriate inspiratory pressure during anesthesia induction via face mask can lead to gastric insufflation.
- Optimizing pressure settings is crucial for patient safety during mechanical ventilation.
- Ultrasonography offers a non-invasive method to assess gastric volume changes.
Purpose of the Study:
- To compare the effectiveness of 12 cm H₂O versus 16 cm H₂O inspiratory pressure during pressure-controlled face mask ventilation.
- To determine the impact of these pressures on gastric insufflation in pediatric patients.
- Primary objective: Measure and compare the cross-sectional area (CSA) of the gastric antrum using ultrasonography.
Main Methods:
- A comparative randomized trial involving 40 children under five years old undergoing general anesthesia.
- Participants received face mask ventilation for four minutes at either 12 cm H₂O (Group P12) or 16 cm H₂O (Group P16) inspiratory pressure.
- Gastric antrum CSA was measured via ultrasonography before and after ventilation; respiratory and hemodynamic parameters were also recorded.
Main Results:
- Both groups showed an increase in gastric antrum CSA post-ventilation.
- Group P16 demonstrated a significantly greater increase in antrum CSA (1.09 to 1.53 cm², p=0.001) compared to Group P12 (1.13 to 1.24 cm², p=0.214).
- The intergroup difference in antral CSA post-ventilation was significant (p=0.035); Group P16 also delivered excessive tidal volumes (9-10 ml/kg).
Conclusions:
- An inspiratory pressure of 16 cm H₂O during face mask ventilation leads to greater gastric antrum distension in children compared to 12 cm H₂O.
- The 12 cm H₂O pressure setting is sufficient for adequate ventilation while minimizing gastric insufflation.
- Lower inspiratory pressure (12 cm H₂O) is recommended for pressure-controlled face mask ventilation in pediatric anesthesia induction.
Related Concept Videos
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation...
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Mechanical Ventilation I: Indication and Settings
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Assessment of Ventilation II: Respiratory Depth and Rhythm
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
Assessment of Ventilation I: Respiratory Rate
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:

