Tobacco Smoking Was Positively Associated with Disease Relapse at week 24 and 48 Among Patients with Psoriasis Vulgaris in Shanghai: A Prospective Study
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View abstract on PubMed
Summary
This summary is machine-generated.Tobacco smoking significantly increases psoriasis relapse rates, particularly for patients with longer smoking duration and higher daily consumption. Quitting smoking is recommended to reduce the risk of psoriasis recurrence.
Area Of Science
- Dermatology
- Public Health
- Epidemiology
Background
- Psoriasis is a chronic inflammatory skin condition.
- Tobacco smoking is a known risk factor for psoriasis onset and severity.
- Limited evidence exists on smoking's impact on psoriasis relapse.
Purpose Of The Study
- To investigate psoriasis relapse rates in patients.
- To explore the association between tobacco smoking and psoriasis relapse.
Main Methods
- An observational study of 551 psoriasis patients was conducted from 2022-2024.
- Data collected via questionnaire and physical examination at baseline and follow-ups (weeks 12, 24, 48).
- Psoriasis Area and Severity Index (PASI) scores used to assess improvement and define relapse (loss of 50% PASI improvement).
Main Results
- 51.2% of patients were smokers; 75.7% were male; average age was 45.8 years.
- Higher relapse rates observed in smokers, especially those achieving PASI75 at week 12 (OR 2.10 at week 24, OR 1.84 at week 48).
- Longer smoking duration and higher daily cigarette consumption correlated with increased relapse risk.
Conclusions
- Tobacco smoking is positively correlated with psoriasis relapse.
- Quitting smoking is advised for psoriasis patients to mitigate relapse risk.
- Further research into smoking cessation interventions for psoriasis management is warranted.
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