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Nanomaterial-Enhanced Dentistry: A Clinical Perspective
Selvam Manoj1, Radhakrishnan Sreena1,2, Rajkumar Divya1,3
1Centre for Biomaterials, Cellular and Molecular Theranostics (CBCMT), Vellore Institute of Technology (VIT), Vellore 632014, Tamil Nadu, India.
ACS Biomaterials Science & Engineering
|July 21, 2025
Summary
Nanotechnology, or nanodentistry, offers advanced solutions for dental diseases, overcoming limitations of conventional treatments. This review explores nanomaterial applications, challenges, and future prospects in dentistry for improved oral health.
Area of Science:
- Biomaterials Science
- Nanotechnology
- Dental Science
Background:
- Billions suffer from dental diseases, with conventional treatments having limitations.
- Nanotechnology offers novel materials with enhanced properties for dentistry.
- Nanodentistry aims for effective, infection-less dental treatments using nanomaterials.
Purpose of the Study:
- To provide a comprehensive overview of nanodental applications.
- To discuss current commercial nanoproducts in dentistry.
- To examine translational challenges and future prospects of nanomaterials in various dental specialties.
Main Methods:
- Literature review of current nanodental applications.
- Analysis of commercialized nanodental products.
- Discussion of challenges and future directions for nanomaterial integration.
Main Results:
- Nanomaterials show significant promise for improving dental materials and treatments.
- Several nanodental products are emerging, but clinical translation faces hurdles.
- A comprehensive overview of applications across dental specialties is lacking.
Conclusions:
- Nanodentistry holds great potential for revolutionizing dental care.
- Addressing translational challenges is crucial for widespread clinical adoption.
- Future research should focus on integrating nanomaterials across diverse dental fields.

