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Validation of a New Anesthesia Technique for Invasive Treatment in the Forehead and Temple: A Split-Face Randomized
Sung Ok Hong1, Hyo-Sang Ahn2, Hyewon Hu3
1From the Department of Oral and Maxillofacial Surgery, Kyung Hee University Dental Hospital at Gangdong.
Plastic and Reconstructive Surgery
|July 21, 2025
Summary
A new superficial injection technique for the zygomaticotemporal nerve (ZTn) significantly reduces pain compared to the conventional deep injection method. This novel approach offers a less painful alternative for temporal anesthesia in aesthetic procedures.
Area of Science:
- Anesthesiology
- Anatomy
- Medical Imaging
Background:
- Conventional zygomaticotemporal nerve (ZTn) anesthesia requires deep insertion, leading to significant patient discomfort.
- A superficial ZTn (sZTn) has been identified, potentially offering a less painful injection method.
- Ultrasonography is crucial for anatomical assessment and guiding novel injection techniques.
Purpose of the Study:
- To compare the efficacy and patient experience of a novel superficial ZTn injection technique against the conventional deep ZTn method.
- To evaluate differences in anesthesia area, pain intensity (Visual Analogue Scale - VAS), and anatomical variations using ultrasonography.
Main Methods:
- A split-face randomized study involving 24 adult patients.
- Ultrasonography was used to determine nerve depth and guide injections.
- Lidocaine with epinephrine was administered via conventional and novel superficial ZTn techniques; outcomes were assessed using VAS, skin temperature, and sensory tests.
Main Results:
- The novel superficial ZTn injection technique resulted in significantly lower mean VAS pain scores (2.4 ±1.1) compared to the conventional method (3.7 ± 1.1).
- Statistically significant differences were observed in touch sensation and skin temperature between the two injection techniques.
- The study included 19 females and 5 males, with an average age of 29.3 ± 3.7 years.
Conclusions:
- The novel superficial ZTn injection technique provides comparable anesthetic effects to the conventional method but with significantly reduced injection pain.
- This technique is a viable and less painful option for achieving anesthesia in the temporal area for aesthetic procedures.

