Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
Derivatives: Problem Solving01:26

Derivatives: Problem Solving

Temperature-Dependent Growth of Brook TroutThe growth of brook trout is closely influenced by water temperature. Experimental data demonstrate how trout weight changes over a 24-day period in response to varying water temperatures. At lower temperatures, such as 15.5 degrees Celsius, brook trout show significant weight gain. However, as the temperature increases, the amount of weight gained steadily decreases. At the highest temperature measured, 24.4 degrees Celsius, trout experience a net...
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Reservoir of Infection01:30

Reservoir of Infection

Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...
Malaria01:29

Malaria

Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Uncovering correlates of decline and critical refuges for a threatened terrestrial mammal.

Conservation biology : the journal of the Society for Conservation Biology·2026
Same author

Fencing the Flux: Seasonal Trends, Environmental Drivers, and Mitigation Opportunities of Methane Emissions From Farm Dams.

Global change biology·2025
Same author

Evolution of research on global amphibian declines.

Conservation biology : the journal of the Society for Conservation Biology·2025
Same author

Land tenure contributions to protected area growth under alternative conservation targets in the Australian monsoon tropics.

Conservation biology : the journal of the Society for Conservation Biology·2025
Same author

Enhancing Farm Dams Increases Tadpole Abundance.

Ecology and evolution·2025
Same author

Multiple Long-Term, Landscape-Scale Data Sets Reveal Intraspecific Spatial Variation in Temporal Trends for Bird Species.

Ecology letters·2024
Same journal

A predisposing effect of HLA class II genes in celiac disease by skewing the naive CD4<sup>+</sup> T cell receptor repertoire.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Wave propagation in fluid-saturated nanoporous media: Upscaling molecular mechanics into continuum-level description.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Collagen-producing eye cell atlas reveals distinct fibroblast fates in early injury vs. fibrotic subretinal disease.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Knotted solid tori in contact manifolds.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Biophysical fitness landscape design traps viral evolution.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Cryo-EM of the eukaryotic purine transporter UapA demonstrates intramolecular and lipid regulation of transport.

Proceedings of the National Academy of Sciences of the United States of America·2026
See all related articles

Related Experiment Video

Updated: Jun 12, 2026

Using Terminal Transferase-mediated dUTP Nick End-labelling TUNEL and Caspase 3/7 Assays to Measure Epidermal Cell Death in Frogs with Chytridiomycosis
07:37

Using Terminal Transferase-mediated dUTP Nick End-labelling TUNEL and Caspase 3/7 Assays to Measure Epidermal Cell Death in Frogs with Chytridiomycosis

Published on: May 16, 2018

10.7K

Thermal mismatch models derived from occurrence data predict pathogen prevalence in frogs.

Richard P Duncan1, Ben C Scheele2, Simon Clulow1

  • 1Centre for Conservation Ecology and Genomics, Institute for Applied Ecology, University of Canberra, Bruce, ACT 2617, Australia.

Proceedings of the National Academy of Sciences of the United States of America
|July 21, 2025
PubMed
Summary
This summary is machine-generated.

The environmental tolerance mismatch hypothesis (ETMH) was supported by a study on the amphibian chytrid fungus (Bd). Thermal niche mismatches between hosts and pathogens predict Bd prevalence in Australian frogs.

Keywords:
Batrachochytrium dendrobatidischytrid fungus, amphibianemerging pathogensenvironmental tolerance mismatch hypothesishost–pathogen interactions

More Related Videos

Determining Temperature Preference of Mosquitoes and Other Ectotherms
05:31

Determining Temperature Preference of Mosquitoes and Other Ectotherms

Published on: September 28, 2022

2.5K
Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
05:08

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins

Published on: July 8, 2025

368

Related Experiment Videos

Last Updated: Jun 12, 2026

Using Terminal Transferase-mediated dUTP Nick End-labelling TUNEL and Caspase 3/7 Assays to Measure Epidermal Cell Death in Frogs with Chytridiomycosis
07:37

Using Terminal Transferase-mediated dUTP Nick End-labelling TUNEL and Caspase 3/7 Assays to Measure Epidermal Cell Death in Frogs with Chytridiomycosis

Published on: May 16, 2018

10.7K
Determining Temperature Preference of Mosquitoes and Other Ectotherms
05:31

Determining Temperature Preference of Mosquitoes and Other Ectotherms

Published on: September 28, 2022

2.5K
Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
05:08

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins

Published on: July 8, 2025

368

Area of Science:

  • Ecology
  • Wildlife disease
  • Pathogen-host interactions

Background:

  • Emerging infectious diseases pose significant threats to wildlife populations.
  • Pathogen impacts vary within and among host species, influenced by environmental conditions.
  • The environmental tolerance mismatch hypothesis (ETMH) posits that host and pathogen performance under varying environmental conditions drives this variability.

Purpose of the Study:

  • To test the ETMH by examining the relationship between thermal niche mismatch and the prevalence of the amphibian fungal pathogen *Batrachochytrium dendrobatidis* (Bd).
  • To assess if thermal mismatch can predict Bd prevalence within and among Australian frog species.
  • To explore the utility of species occurrence data for predicting pathogen outcomes.

Main Methods:

  • Derived species realized thermal niches from occurrence data for 42 Australian frog species.
  • Quantified thermal mismatch between frog hosts and the Bd pathogen.
  • Analyzed the relationship between thermal mismatch and Bd prevalence within and among species.

Main Results:

  • Thermal mismatch reliably predicted variation in Bd prevalence across Australian frog species.
  • Within species, warmer-adapted hosts exhibited a steeper decline in Bd prevalence with increasing temperature.
  • Among species, higher pathogen prevalence was associated with closer thermal affinities between hosts and the pathogen.

Conclusions:

  • Findings strongly support the ETMH, demonstrating its applicability in predicting wildlife disease dynamics.
  • Thermal niche mismatch, derived from occurrence data, is a robust predictor of pathogen prevalence.
  • This approach offers a valuable tool for spatial and temporal prediction of pathogen impacts and can inform conservation strategies.