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Pharmacovigilance01:19

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Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
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Drug Administration and Therapy Phases: Overview01:26

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Drugs, the chemical agents used in diagnosing, treating, or preventing diseases, undergo a four-phase process of development: pharmaceutic, pharmacokinetics, pharmacodynamics, and therapeutic.
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Drug Therapy01:28

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The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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Preclinical Development: Overview01:28

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Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
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Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
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Drug Regulation01:25

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Practice-enhancing publications about the medication-use process in 2024.

Tyler A Vest1, Daniel P O'Neil2, Nicholas P Gazda3

  • 1University of Vermont Health Network, Burlington, VT, and University of North Carolina at Chapel Hill Eshelman School of Pharmacy, Chapel Hill, NC, USA.

American Journal of Health-System Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
|July 21, 2025
PubMed
Summary
This summary is machine-generated.

This review highlights key 2024 literature impacting the medication-use process (MUP) in health-system pharmacy. It identifies 45 practice-enhancing articles across prescribing, dispensing, administration, and monitoring for improved patient safety.

Keywords:
administrationcomputerized prescriber order entrydispensingmedication use processmonitoringprescribing

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Area of Science:

  • Pharmacy Practice
  • Health Systems
  • Medication Safety

Background:

  • The medication-use process (MUP) is critical for safe medication utilization in healthcare.
  • Understanding recent advancements in the MUP is essential for health-system pharmacy practice improvement.

Purpose of the Study:

  • To identify, prioritize, and summarize 2024 literature impacting the medication-use process (MUP).
  • To assess the usefulness of evaluated articles for health-system pharmacy practice improvement.

Main Methods:

  • A comprehensive literature search was conducted in PubMed and selected pharmacy journals for articles published in 2024.
  • Articles were screened for relevance to the MUP components: prescribing/transcribing, dispensing, administration, and monitoring.

Main Results:

  • A total of 5,893 articles were initially identified, with 45 selected as practice-enhancing.
  • These 45 articles were categorized: 10 on prescribing/transcribing, 15 on dispensing, 8 on administration, and 12 on monitoring.

Conclusions:

  • Routinely reviewing literature on the MUP is crucial for incorporating significant findings into daily practice.
  • Health-system pharmacists can leverage this summarized research to drive institutional practice changes and enhance medication safety.