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Uncertainty: Overview00:59

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In analytical chemistry, we often perform repetitive measurements to detect and minimize inaccuracies caused by both determinate and indeterminate errors. Despite the cares we take, the presence of random errors means that repeated measurements almost never have exactly the same magnitude. The collective difference between these measurements - observed values - and the estimated or expected value is called uncertainty. Uncertainty is conventionally written after the estimated or expected value.
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Uncertainty in Measurement: Accuracy and Precision03:37

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Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value. 
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The confidence interval is the range of values around the mean that contains the true mean. It is expressed as a probability percentage. The interpretation of a 95% confidence interval, for instance, is that the statistician is 95% confident that the true mean falls within the interval. The upper and lower limits of this range are known as confidence limits. The confidence limits for the true mean are estimated from the sample's mean, the standard deviation, and the statistical factor...
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Estimation-uncertainty affects decisions with and without learning opportunities.

Kristoffer C Aberg1,2, Levi Antle3,4, Rony Paz5,6

  • 1Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel. kc.aberg@gmail.com.

Nature Communications
|July 21, 2025
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Summary
This summary is machine-generated.

Estimation-uncertainty, how often an option is sampled, influences long-term decisions even without new learning opportunities. This sampling bias persists, impacting choices independently of expected outcomes in reinforcement learning.

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Area of Science:

  • Cognitive Neuroscience
  • Behavioral Economics
  • Computational Neuroscience

Background:

  • Reinforcement learning (RL) involves outcome expectations and estimation-uncertainty, which influences exploration.
  • The long-term impact of estimation-uncertainty on decisions without further learning or exploration remains unclear.

Purpose of the Study:

  • To investigate if estimation-uncertainty from a reinforcement learning phase affects subsequent decisions without feedback.
  • To determine if this effect is independent of outcome expectations.

Main Methods:

  • A reinforcement learning phase with feedback was conducted.
  • A subsequent test phase without feedback assessed decision biases.
  • Computational modeling was used to fit behavioral data.

Main Results:

  • Sampling rates acquired during learning correlated with decision biases in the test phase.
  • Estimation-uncertainty improved computational model fits, especially for less-sampled options.
  • Findings were replicated across two independent datasets.

Conclusions:

  • Estimation-uncertainty acquired during reinforcement learning can create lasting decision biases.
  • This bias operates independently of outcome expectations.
  • Estimation-uncertainty is a crucial factor in understanding human decision-making.