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Pediatric non-alcoholic Wernicke's encephalopathy: a case report
Lucia Corso1, Laura Lucaccioni2,3, Martina Buttera1
1Postgraduate School of Paediatrics, University of Modena and Reggio Emilia, Modena, Italy.
Italian Journal of Pediatrics
|July 21, 2025
Summary
Wernicke
Area of Science:
- Neurology
- Nutritional Neuroscience
Background:
- Wernicke-Korsakoff syndrome is a neurological disorder from thiamine deficiency.
- While often linked to alcoholism, non-alcoholic causes exist, including in children.
Observation:
- An 11-year-old obese male developed Wernicke's encephalopathy symptoms after bariatric surgery complications and a hypocaloric diet.
- Symptoms included visual impairment, nystagmus, and diplopia, indicating acute thiamine deficiency.
Findings:
- Prompt empiric thiamine supplementation led to significant clinical improvement.
- This case highlights risk factors for non-alcoholic Wernicke's encephalopathy in pediatric patients.
Implications:
- Early recognition and treatment of non-alcoholic Wernicke's encephalopathy are crucial for favorable outcomes.
- Increased awareness of pediatric risk factors can improve diagnostic rates and patient survival.

