Related Experiment Video
Updated: Sep 14, 2025
A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol
Published on: January 18, 2018
Evidence on vaping e-cigarettes as a risk factor for cancer: A systematic review
Guilherme Guedes de Oliveira1, Rebeca Milka Lemos Magalhães Liberato1, Amaxsell Thiago Barros de Souza2
1Department of Medicine, Potiguar University, Natal, Brazil.
Objective:
This review aims to evaluate the association between e-cigarette use and cancer risk.
Study Design:
A systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement.
Methods:
Studies were sourced from PubMed/MEDLINE, LILACS, Embase, Web of Science, and Scopus up to September 2024. Observational studies evaluating the association between e-cigarette use and cancer risk were included. Data selection and extraction were performed independently and in pairs. The risk of bias was assessed using the Newcastle-Ottawa Scale (NOS) for cohort and case-control studies and the Joanna Briggs Institute (JBI) critical appraisal tool for cross-sectional studies.
Results:
Ten studies were included in the final analysis, a total of 143,975 patients. Skin cancer represented 7 % (n = 635) of cases, followed by breast cancer at 4 % (n = 370), prostate cancer at 2 % (n = 234), melanoma at 1.4 % (n = 118), and colon cancer 1.2 % (n = 106). A single study identified associations between e-cigarette use and various types of cancer, along with links to lung disease, depression, and physical inactivity. Another study suggested a potential association between e-cigarette use and lung cancer, as well as a later-stage diagnosis for breast and colorectal cancers. However, three studies found no significant link between e-cigarette use and non-muscle-invasive bladder cancer.
Conclusion:
E-cigarette use may be associated with an increased risk of certain cancers, including cervical and breast cancer. However, the evidence remains inconclusive, and more rigorous longitudinal studies are needed to provide clearer conclusions.
More Related Videos
08:39Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
Published on: August 25, 2018
10:44Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
Related Concept Videos
01:29Stimulants
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
02:59Cancer Prevention
Some...
01:28Criteria for Causality: Bradford Hill Criteria - II
01:25Statistical Methods for Analyzing Epidemiological Data
02:49Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
01:30Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...