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Primary Tumor and MEF Cell Isolation to Study Lung Metastasis
Published on: May 20, 2015
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Breast metastasis from lung cancer
Najla Bahloul1, Wala Ben Kridis2, Ilhem Yangui1
1Department of Pulmonology, Hedi Chaker University Hospital of Sfax, Sfax, Tunisia.
Indian Journal of Thoracic and Cardiovascular Surgery
|July 22, 2025
Summary
Metastatic lung cancer to the breast is rare, occurring in 0.2-1.3% of cases. Clinicians should consider lung cancer metastasis in breast nodules of lung cancer patients.
Area of Science:
- Oncology
- Pulmonology
- Radiology
Background:
- Breast metastases from extra-mammary cancers are uncommon, accounting for 0.4-6% of malignant breast tumors.
- Mammary metastases from lung cancer are exceptionally rare, with published cases being few.
- The incidence of lung cancer metastasis to the breast is estimated between 0.2-1.3%.
Purpose of the Study:
- To report an extremely rare case of lung cancer metastasis to the breast.
- To highlight the importance of considering lung cancer as a differential diagnosis for breast nodules.
Main Methods:
- Case report presentation.
- Review of relevant literature.
Main Results:
- The case presented is the first documented instance of lung cancer metastasis to the breast in North Africa.
- The study underscores the diagnostic challenge posed by such rare presentations.
Conclusions:
- Clinicians must consider metastatic lung cancer in patients with breast nodules, especially those with a history of lung cancer.
- Early recognition of lung cancer metastasis to the breast is crucial for appropriate patient management.

