Phonologic agraphia in a left-handed patient after a right-hemisphere lesion

Oral and written spelling were evaluated in a left-handed patient with a right-hemisphere infarct and right-hemisphere language representation. Spelling was intact for different classes of words, but there was severe difficulty in both oral and written spelling of nonwords. This pattern was consistent with phonologic agraphia. There was selective disruption of the segmentation component, with intact phoneme-to-grapheme conversion supporting the Roeltgen and Heilman hypothesis of two-system spelling after lesions in the left supramarginal gyrus. This is the first case of phonologic agraphia after right supramarginal gyrus damage in a left-handed patient.