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Updated: May 10, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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The Burden of Pediatric Psoriasis: A Systematic Review

Angela Yang1,2, Brian Cheng1,2, Marieke M B Seyger3

  • 1Department of Dermatology, Northwestern University Feinberg School of Medicine, 676 N St Clair, Suite 1600, Chicago, IL, 60611, USA.

American Journal of Clinical Dermatology
|July 22, 2025
PubMed

Insights

Pediatric psoriasis significantly impacts children's quality of life and causes physical symptoms like itch. The condition also burdens caregivers mentally and financially, necessitating comprehensive assessment.

Area of Science:

  • Dermatology
  • Pediatrics
  • Psychology

Background:

  • Pediatric psoriasis presents unique challenges due to potential physical and psychosocial health impacts.
  • Specialized approaches are crucial for managing childhood psoriasis effectively.

Purpose of the Study:

  • To systematically review existing literature and define the multifaceted burden of pediatric psoriasis.
  • To identify key areas of impact, including quality of life, physical symptoms, and psychosocial effects.

Main Methods:

  • A comprehensive literature search was conducted across multiple databases (Ovid MEDLINE, CENTRAL, Cochrane, PsycInfo) up to July 2023.
  • Studies focusing on children under 18 with psoriasis were included if they assessed quality of life, physical, psychological, social, or financial effects.
  • Exclusion criteria included comorbidities, low-quality studies, and non-English articles.

Main Results:

  • 64 publications were analyzed, with quality of life being the most studied domain, negatively correlated with psoriasis severity.
  • Physical burdens, particularly itch (44.1-96.3%), were prevalent; skin pain was less common.
  • Psychosocial and family burdens were less assessed, though psoriasis was linked to reduced social activity, increased caregiver mental health burden, and financial strain.

Conclusions:

  • Pediatric psoriasis imposes a substantial burden on both patients and their families, including caregivers.
  • Integrating comprehensive burden assessments into clinical evaluation and management is essential.
  • Further research with validated tools is needed to fully understand psychosocial and family impacts.
Abstract

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