Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

95
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
95
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

58
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
58
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

76
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
76
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

101
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
101
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

74
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
74
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

80
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
80

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of Trimethoprim on Three Previously Proposed Putative Biomarkers for OCT2/MATE-Mediated Renal Drug-Drug Interactions in Healthy Volunteers.

Clinical pharmacology and therapeutics·2026
Same author

Young Investigator Award 2026: Extent and incidence of pseudo-worsening of kidney function due to oral antitumor therapeutics in the AMBORA cohort: an analysis of real-world data.

Naunyn-Schmiedeberg's archives of pharmacology·2026
Same author

Development of phenotype algorithms for the detection of adverse events in electronic health record data: a multicentre study.

BMJ open·2026
Same author

Deorphanisation and functional characterisation of OATP5A1 as transport protein for amino acids and vitamins.

Cellular & molecular biology letters·2026
Same author

Secondary Data for Clinical Pharmacists' Decision Support: Evaluating 'Triple Whammy' Interactions Within INTERPOLAR.

Studies in health technology and informatics·2026
Same author

Therapeutic Drug Monitoring of Imatinib in Paediatric Chronic Myeloid Leukaemia: Towards Practical Implementation and Interpretation of Measured Plasma Concentrations.

Clinical pharmacokinetics·2026

Related Experiment Video

Updated: Sep 14, 2025

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
06:38

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats

Published on: March 11, 2016

12.2K

Pseudo-Worsening of Kidney Function

Martin F Fromm, Michael I Sponfeldner, Frank Dörje

    Deutsches Arzteblatt International
    |July 22, 2025
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis
    04:37

    Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis

    Published on: April 25, 2025

    781
    5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
    05:34

    5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

    Published on: April 4, 2025

    857

    Related Experiment Videos

    Last Updated: Sep 14, 2025

    Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
    06:38

    Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats

    Published on: March 11, 2016

    12.2K
    Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis
    04:37

    Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis

    Published on: April 25, 2025

    781
    5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
    05:34

    5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

    Published on: April 4, 2025

    857