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Updated: Sep 14, 2025

Author Spotlight: Scaling Microalgal Biotechnology for Enhanced Biomethane Production
Published on: March 22, 2024
Unlocking the algae toolbox: Cutting-edge tools for environmental and biotechnological solutions
Vu Khac Hoang Bui1, Le Gia Trung2, Ha Huu Do3
1Laboratory for Advanced Nanomaterials and Sustainable Energy Technologies, Institute for Computational Science and Artificial Intelligence, Van Lang University, Ho Chi Minh City, Viet Nam; Faculty of Applied Technology, School of Technology, Van Lang University, Ho Chi Minh City, Viet Nam.
Abstract:
Algae are highly adaptable photosynthetic organisms with growing relevance in biotechnology, environmental management, and sustainable industries. Recent advancements have expanded the "Algae Toolbox", integrating cutting-edge screening, monitoring, characterization, and large-scale production technologies. This current work critically examines the latest developments in algal research, including CRISPR-Cas9 genetic engineering, high-throughput omics, machine learning-driven modeling, and remote sensing-based ecosystem monitoring. Moreover, innovations in optical sensors, flow cytometry, biosensors, and environmental DNA have further improved precision in tracking algal dynamics. These advances support industrial scale-up, boosting productivity and sustainability in biofuels, pharmaceuticals, aquaculture, and bioremediation. However, large-scale production still faces challenges in economic viability and environmental sustainability. Future research must incorporate artificial intelligence, internet of things-enabled sensing, and synthetic biology for optimized cultivation and bioproduct harvesting. This review provides a comprehensive overview of emerging tools and methodologies, emphasizing their role in advancing algal biotechnology and global sustainability.
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