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Pruritus and Unkempt Coat in a New Zealand White Rabbit (Oryctolagus cuniculus)

Diana E Hasler1, Jarukit E Long2, Kourtney P Nickerson2

  • 11Unit for Laboratory Animal Medicine, University of Michigan, Ann Arbor, Michigan.

Journal of the American Association for Laboratory Animal Science : JAALAS
|July 22, 2025
PubMed
Abstract

No abstract available in PubMed .

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Epistasis

In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
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