Related Experiment Video
Updated: May 10, 2026

Co-culture of Glutamatergic Neurons and Pediatric High-Grade Glioma Cells Into Microfluidic Devices to Assess Electrical Interactions
Published on: November 17, 2021
Dentinogenic ghost cell tumor in a pediatric patient: A case report and literature review
Müjde Gürsu1, Mehmet Altay Sevimay1, Ertuğrul Çekmez1
1Department of Oral and Maxillofacial Surgery, Gazi University Faculty of Dentistry, Ankara, Turkey.
Rationale:
Dentinogenic ghost cell tumors (DGCTs) are rare odontogenic neoplasms constituting the solid variant of calcifying odontogenic cysts. Predominantly observed in adults, DGCTs are exceptionally rare in pediatric patients. This case report aims to contribute to the limited literature by presenting the clinical, radiographic, and histopathological findings of a pediatric patient with a DGCT and emphasizing the importance of early diagnosis.
Patient Concerns:
A 14-year-old male presented with facial asymmetry in the left mandible.
Diagnoses:
Diagnostic imaging revealed a multilocular radiolucent lesion with impacted teeth, cortical expansion, and root resorption. Histopathological evaluation confirmed the DGCT diagnosis.
Interventions:
The lesion was treated conservatively with enucleation and curettage, followed by a 3-year follow-up.
Outcomes:
Regular follow-ups demonstrated progressive bone regeneration with no evidence of recurrence. No postoperative complications were observed.
Lessons:
Because of their high recurrence rate and potential for transformation into dentinogenic ghost cell carcinoma, early diagnosis and long-term follow-up are crucial for effective management in DGCT cases.

