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Updated: Sep 14, 2025

Synthesis of Keratin-based Nanofiber for Biomedical Engineering
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Bioinspired micro-structured fibers for biomedical applications.

Jiahui Guo1, Shuangshuang Miao2, Lingyu Sun2

  • 1Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, 226001, China.

Bioactive Materials
|July 23, 2025
PubMed
Summary
This summary is machine-generated.

This review summarizes advancements in bioinspired fibers, mimicking natural materials like spider silk. These engineered fibers offer diverse microstructures and promising biomedical applications.

Keywords:
BioinspiredBiomedicineMicrofiberMicrofluidicsMicrostructure

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Last Updated: Sep 14, 2025

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Area of Science:

  • Materials Science
  • Biomaterials Engineering
  • Textile Science

Background:

  • Fibers are ubiquitous in nature and human industry, from textiles to medicine.
  • Nature, particularly spider and silkworm spinning, inspires advanced bioinspired fiber materials.
  • These materials feature diverse microstructures and significant potential.

Purpose of the Study:

  • To review the latest progress in the structures and applications of bioinspired fibers.
  • To highlight fabrication methods and characterization techniques for tailored bioinspired fibers.
  • To summarize biomedical applications and future challenges/opportunities.

Main Methods:

  • Literature review of natural fiber systems (e.g., spider silk, silkworm silk, muscle).
  • Analysis of fabrication methods for creating bioinspired fibers with specific structures.
  • Compilation of characterization techniques used for these advanced materials.

Main Results:

  • Significant progress in designing bioinspired fibers with controlled microstructures.
  • Demonstrated potential of these fibers in various biomedical applications.
  • Identification of key fabrication and characterization approaches.

Conclusions:

  • Bioinspired fibers represent a rapidly advancing field with broad applicability.
  • Further research is needed to overcome challenges and realize future opportunities in fiber development.
  • Tailored bioinspired fibers hold promise for innovative solutions in medicine and beyond.