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Updated: Sep 14, 2025

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
Relationship and sexual satisfaction among patients with bipolar disorder and partners
Lærke Helene Andreasen1,2, Vita Djamilla Sandeman1,2, Helle B Krogh1,3
1Sexological Clinic, Copenhagen University Hospital - Mental Health Services CPH, Ole Maaløes Vej 14, 2100 Copenhagen, Denmark.
Objectives:
Good interpersonal relationships are associated with improved functioning, quality of life, and a better prognosis in patients with bipolar disorder (BD). Little information is available regarding relationship satisfaction and sexual satisfaction within couples where 1 partner has BD.
Aim:
This cross-sectional study aimed to examine relationship and sexual satisfaction in patients with BD and partners to patients with BD.
Methods:
Patients with BD and partners to patients with BD were included, and outcomes were assessed using semi-structured interviews and questionnaires.
Outcomes:
Couple satisfaction was measured by the self-reported questionnaire Couple Satisfaction Index (CSI-4), and sexual satisfaction was measured by 3 self-reported questions. Multiple regression analyses were used to compare the groups adjusting for sex, age, mood symptoms, overall functioning, and stress symptoms. The results were compared to general populations.
Results:
One hundred eleven patients with BD and 74 partners were included. We found a significant difference between patients with BD and partners concerning relationship satisfaction measured with the CSI, with partners being less satisfied (P = .050). Comparing relationship satisfaction in patients with BD and partners to the general population, we found that the general population was more satisfied in each CSI item (P < .050). In multiple regression analyses adjusted for sex, age, mood symptoms, stress, and function, patients with BD were more satisfied with their sexual life over the last year compared to partners (P = .039). They further rated the importance of a good sexual life higher than partners (P = .006). Finally, more patients with BD and partners rated their sex life the last year as being bad to extremely bad compared to the control group from the general population (partners = 21.1%, BD = 23.4%, general population = 16%).
Clinical Implications:
In clinical practice, it is essential to focus on relationships including sexual life in patients with BD and partners as both groups have a lower degree of relationship and sexual satisfaction compared to the general population.
Strengths And Limitations:
The use of validated questionnaires and clinical ratings is a strength, albeit the cross-sectional design is a limitation.
Conclusions:
Patients with BD reported a higher degree of satisfaction with their relationship and sexual life compared to their partners. Compared to the general population, both groups expressed lower degree of relationship and sexual satisfaction.
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