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Updated: Sep 14, 2025

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Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
Published on: May 16, 2022
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Biophotonic (nano)structures: from fundamentals to emerging applications
Masoomeh Amoozadeh1, Amirali Hariri2, Atefeh Zarepour3,4
1Department of Chemistry, University of Isfahan Isfahan 81746 Iran.
RSC Advances
|July 23, 2025
Summary
Biophotonics uses light to explore biological systems, with nanostructures enhancing medical imaging, diagnostics, and therapies. Overcoming challenges in fabrication and biocompatibility will unlock its full potential in healthcare.
Area of Science:
- Biophotonics, an interdisciplinary field merging biology and optics.
- Focuses on light-based exploration and manipulation of biological systems.
Background:
- Biophotonic nanostructures are crucial for medical imaging, diagnostics, and therapy.
- Applications include enhanced imaging, disease marker detection (biosensing), and advanced therapeutic approaches.
Purpose of the Study:
- To review biophotonic nanostructures and their applications in disease diagnosis, imaging, and therapy.
- To examine challenges and future directions in biophotonic research.
Main Methods:
- Review of existing literature on biophotonic nanostructures.
- Analysis of applications in medical diagnostics, imaging, and therapy.
- Discussion of fabrication, scalability, biocompatibility, and integration challenges.
Main Results:
- Biophotonic nanostructures enhance medical imaging, biosensing, and therapeutic interventions (photothermal/photodynamic therapy).
- Key challenges include complex fabrication, scalability, biocompatibility, and integration with existing medical technologies.
- Advancements in nanotechnology (e.g., 3D printing) offer solutions for production.
Conclusions:
- Biophotonics holds significant promise for revolutionizing healthcare through improved diagnostics and therapies.
- Overcoming current challenges is critical for clinical translation and widespread adoption.
- Future integration with wearable devices and point-of-care diagnostics could enable continuous health monitoring.
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