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Sodium Valproate-Induced Gingival Enlargement in a Pediatric Patient: A Case Report With Surgical Intervention
Nezy Varghese1, R Rajesh1, Darsana Krishnan1
1Pediatric and Preventive Dentistry, Indira Gandhi Institute of Dental Sciences, Nellikuzhi, IND.
Abstract:
Gingival enlargement occurs secondary to the usage of anti-epileptics. The severity of overgrowth varies among different classes of drugs, with phenytoin having the highest incidence of reported cases, whereas cases associated with sodium valproate are minimal. Factors like drug dose, genetic factors, plaque, gingival inflammation, and periodontal health influence the degree of overgrowth. This case report presents one of the first surgically managed cases of generalized gingival enlargement in a pediatric patient due to chronic usage of sodium valproate.
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