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Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Cancer Therapies

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...

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Related Experiment Video

Updated: Sep 14, 2025

Synthesis and Characterization of Placental Chondroitin Sulfate A plCSA-Targeting Lipid-Polymer Nanoparticles

Synthesis and Characterization of Placental Chondroitin Sulfate A plCSA-Targeting Lipid-Polymer Nanoparticles

Published on: September 18, 2018

Chitosan-Based Materials: A Comprehensive Review on Anticancer Drug Development.

Faris J Tayeb¹, Mohammed Fareed Felemban², Amal Adnan Ashour³

¹Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, University of Tabuk, Tabuk, Saudi Arabia.

Medicinal Chemistry (Shariqah (United Arab Emirates))

|July 23, 2025

Summary

Chitosan (CT) biomaterials show promise for advanced cancer treatment by improving drug delivery. Modified CT enhances chemotherapy efficacy, reduces toxicity, and combats resistance, offering new therapeutic strategies.

Keywords:

Cancer apoptosis carboxymethylation.chitosan drug delivery

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Last Updated: Sep 14, 2025

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Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo

Published on: February 6, 2015

Area of Science:

Biomaterials Science
Oncology
Drug Delivery Systems

Background:

Cancer is a leading global health threat, necessitating advanced therapies.
Anticancer drugs target critical cellular processes like DNA replication and apoptosis.
Chitosan (CT) is a versatile biomaterial with potential in cancer treatment.

Purpose of the Study:

To review recent (2021-2024) developments in chitosan-based materials for anticancer drug delivery.
To explore the design, mechanisms, and applications of these materials.
To discuss challenges and future directions for clinical translation.

Main Methods:

Review of recent scientific literature (2021-2024) on chitosan-based anticancer drug delivery systems.
Analysis of modifications to chitosan, including carboxymethylation, sulfation, and graft copolymerization.
Evaluation of therapeutic mechanisms, including controlled release, enhanced bioavailability, and targeted delivery.

Main Results:

Chitosan-based materials demonstrate potential for improved drug efficacy and targeted tumor delivery.
Modified chitosan enhances encapsulation of chemotherapeutics, reduces systemic toxicity, and addresses multidrug resistance.
Recent advancements focus on optimizing design principles for therapeutic applications.

Conclusions:

Chitosan-based drug delivery systems offer significant promise for revolutionizing cancer therapy.
Further research and development are needed to overcome challenges in clinical translation.
Optimized chitosan strategies could lead to more effective and safer cancer treatments.