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Labeling DNA Probes

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
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Related Experiment Video

Updated: Sep 14, 2025

A Two-Step Pyrolysis-Gas Chromatography Method with Mass Spectrometric Detection for Identification of Tattoo Ink Ingredients and Counterfeit Products

A Two-Step Pyrolysis-Gas Chromatography Method with Mass Spectrometric Detection for Identification of Tattoo Ink Ingredients and Counterfeit Products

Published on: May 22, 2019

Tattoo Sticker for GHB Detection to Prevent Date Rape.

Gyeong-Ji Kim¹, Jai Eun An^1,2, Jung In Kim³

¹SKKU Advanced Institute of Nanotechnology (SAINT), Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea.

|July 23, 2025

Summary

This summary is machine-generated.

A new wearable tattoo sticker can rapidly detect gamma-hydroxybutyrate (GHB), a substance linked to drug-facilitated sexual assault (DFSA). This noninvasive sensor changes color upon GHB presence, offering real-time monitoring for enhanced personal safety.

Keywords:

GHB chemical receptor BHEI colorimetric sensor tattoo sticker wearable sensor

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Last Updated: Sep 14, 2025

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Skin Tattooing As A Novel Approach For DNA Vaccine Delivery

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Published on: October 18, 2012

Area of Science:

Chemical Sensing
Wearable Technology
Forensic Science

Background:

Gamma-hydroxybutyrate (GHB) is frequently used in drug-facilitated sexual assaults (DFSA).
Current detection methods for GHB can be time-consuming and invasive.
There is a need for rapid, noninvasive methods for GHB detection.

Purpose of the Study:

To develop a wearable tattoo sticker for the rapid, noninvasive detection of GHB.
To integrate a colorimetric sensor into a tattoo-like patch for real-time GHB monitoring.
To assess the durability and practical applicability of the GHB-detecting tattoo sticker.

Main Methods:

Fabrication of a tattoo sticker using polydimethylsiloxane (PDMS), poly(vinyl alcohol) (PVA), and an agarose gel embedded with a GHB-specific receptor (BHEI).
Evaluation of the sensor's colorimetric response to GHB in solution and various beverages.
Testing of the tattoo sticker's mechanical durability, water resistance, adhesion, and scratch resistance.

Main Results:

The developed tattoo sticker successfully detected GHB at concentrations of 0.01 mg/mL and 0.1 mg/mL.
Detection of GHB in various beverages (whisky, vodka, beer, soju, coffee) was achieved within 1 second.
The tattoo sticker demonstrated good mechanical stability and adhesion properties.

Conclusions:

The wearable GHB detection tattoo sticker offers a promising, noninvasive tool for real-time monitoring.
This technology can serve as a proactive measure to help prevent drug-facilitated sexual assaults.
The sticker's ease of use and rapid detection capability empower individuals with enhanced personal safety options.