Artificial intelligence-based model for the interpretation and reporting of standard automated perimetry

Standard automated perimetry has been the standard method for measuring visual field changes for several years. It can measure an individual's ability to detect a light stimulus from a uniformly illuminated background. In the management of glaucoma, the primary objective of perimetry is the identification and quantification of visual field abnormalities. It also serves as a longitudinal evaluation for the detection of disease progression. The development of artificial intelligence--based models capable of interpreting tests could combine technological development with improved access to healthcare.

In this observational, cross-sectional, descriptive study, we used an artificial intelligence-based model [Inception V3] to interpret gray-scale crops from standard automated perimetry that were performed in an ophthalmology clinic in the Brazilian Amazon rainforest between January 2018 and December 2022.

The study included 1,519 standard automated perimetry test results that were performed using Humphrey HFA-II-i-750 (Zeiss Meditech). The Subsequently, 70%, 10%, and 20% of the dataset were used for training, validation, and testing, respectively. The model achieved 80% (68.23%-88.9%) sensitivity and 94.64% (88.8%-98%) specificity for detecting altered perimetry results. Furthermore, the area under the receiver operating characteristic curve was 0.93.

The integration of artificial intelligence in the diagnosis, screening, and monitoring of pathologies represents a paradigm shift in ophthalmology, enabling significant improvements in safety, efficiency, availability, and accessibility of treatment.