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Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
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Transcatheter Structural Heart Interventions in Women
Jina Chung1, Katharine Yang2, Nino Nozadze3
1Division of Cardiology, Department of Medicine, Harbor UCLA Medical Center, 1000 W Carson St. Box 405, Torrance, CA, 90502, USA. jinachung@lundquist.org.
Current Cardiology Reports
|July 23, 2025
Summary
This review examines transcatheter structural heart interventions for women, highlighting sex-specific factors in diagnosis, treatment, and outcomes. It addresses knowledge gaps to improve lifelong care for women with heart disease.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Women's Health
Background:
- Transcatheter structural heart interventions have advanced treatment for valvular heart disease and left atrial appendage closure.
- Historically, limited female participation in trials has hindered sex-specific guideline development.
- Recent increases in female representation offer insights into distinct pathophysiology and treatment responses.
Purpose of the Study:
- To review current transcatheter structural heart interventions in women.
- To focus on sex-specific considerations in diagnosis, treatment, and outcomes.
- To identify knowledge gaps and future research directions for women with structural heart disease.
Main Methods:
- Review of contemporary female representation in transcatheter structural heart intervention studies.
- Evaluation of sex-specific prevalence, variations, and outcomes.
- Identification of diagnostic and therapeutic disparities.
Main Results:
- Transcatheter interventions are transforming structural heart disease care.
- Increased female representation reveals distinct disease characteristics and treatment responses.
- Sex-specific data is crucial for optimizing patient selection and intervention timing.
Conclusions:
- Addressing diagnostic and therapeutic disparities is essential for improving women's heart care.
- Future research should focus on sex-specific aspects of structural heart disease.
- Individualized lifetime care for women with structural heart disease requires further investigation.
Keywords:
Health equitySex-specific differencesStructural heart interventionsTranscatheter interventionsValvular heart diseaseWomen’s cardiovascular diseaseMore Related Videos
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