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Updated: Sep 14, 2025

Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells
Published on: March 16, 2017
Nitric Oxide Regulates Multiple Signal Pathways in Plants via Protein S-Nitrosylation
Wei Lin1, Jian-Xiu Shang2, Xiao-Ying Li2
1School of Biology and Food Science, Hebei Normal University for Nationalities, Chengde 067000, China.
Abstract:
Nitric oxide (NO) can perform its physiological role through protein S-nitrosylation, a redox-based post-translational modification (PTM). This review details the specific molecular mechanisms and current detection technologies of S-nitrosylation. It also comprehensively synthesizes emerging evidence of S-nitrosylation roles in plant biological processes, including growth and development, immune signaling, stress responses and symbiotic nitrogen fixation. Furthermore, the review analyzes research progress on the crosstalk between S-nitrosylation and other protein PTMs. Finally, unresolved issues such as the spatio-temporal resolution of SNO-proteome mapping and standardized protocols for reproducibility are pointed out. In summary, this work proposes a roadmap for future research.
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