Related Experiment Video
Updated: Jul 27, 2026

In Situ Synthesis of Gold Nanoparticles without Aggregation in the Interlayer Space of Layered Titanate Transparent Films
Published on: January 17, 2017
Green biosynthesis of bimetallic silver titanium dioxide nanoparticles using Pluchea indica with their anticancer,
Samy Selim1, Bahaa M Badr2,3, Mohamed H Moustafa4
1Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, Saudi Arabia.
Abstract:
Natural plant extracts provide a cost-effective and eco-friendly option for the synthesis of bimetallic nanoparticles, as opposed to traditional chemical or physical methods. This research involved the bio-fabrication of silver-titanium dioxide bimetallic nanoparticles (Ag-TiO2 BNPs) utilizing the leaf extract of Pluchea indica. The Ag-TiO2 BNPs underwent characterization through UV-vis spectroscopy, FTIR, TEM, XRD, and DLS techniques. The UV-Vis spectroscopy results revealed an absorbance peak at 350 nm, which confirms the successful synthesis of Ag-TiO2 BNPs. TEM observations revealed that the average diameter of the Ag-TiO2 BNPs varied between 10 and 60 nm. The assessment of the anticancer, antibacterial, and antioxidant bioactivities of the biosynthesized Ag-TiO2 BNPs was conducted. Results revealed that the IC50 of Ag-TiO2 BNP against Wi-38 normal cell line was 169.6 µg/mL. Moreover, Ag-TiO2 BNPs exhibited anticancer activity against MCF-7 cancerous cell line with an IC50 of 33.5 µg/mL. Furthermore, the produced Ag-TiO2 BNPs exhibited antibacterial properties against a range of pathogenic bacterial strains, with MIC varying from 31.25 to 62.5 µg/mL. Additionally, Ag-TiO2 BNPs showed antioxidant activity with IC50 225 µg/mL. In conclusion, Ag-TiO2 BNPs was successfully biosynthesized using P. indica leaves, where it had anticancer, antibacterial, and antioxidant properties.
More Related Videos
11:19Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties
Published on: May 10, 2018
11:16Preparation of Silver-Palladium Alloyed Nanoparticles for Plasmonic Catalysis under Visible-Light Illumination
Published on: August 18, 2020
Related Concept Videos
Green Algae
Microbial Bioremediation of Uranium
iChip
Bioplastics
Microbial Bioremediation of Plastics