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Updated: Sep 14, 2025

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Autologous Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus
Published on: January 23, 2018
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Clinical short-term analysis and effectiveness evaluation of optimally designed customized artificial talus implants
Yeokyung Kang1, Kwang Hwan Park2, Jin Woo Lee2
1Central Research & Development Center, Corentec Co., Ltd., Seoul, Republic of Korea.
Scientific Reports
|July 23, 2025
Summary
This study introduces a 3D-printed total talar implant for avascular necrosis (AVN) of the talus. Early results show improved pain and function, suggesting potential for joint preservation in advanced talar AVN patients.
Area of Science:
- Orthopedic Surgery
- Biomedical Engineering
- Radiology
Background:
- Avascular necrosis (AVN) of the talus is a rare condition leading to joint collapse.
- Advanced talar AVN has limited joint-preserving surgical options.
- Patient-specific implants offer potential for tailored treatment.
Purpose of the Study:
- Develop a lightweight, patient-specific 3D-printed total talar implant.
- Evaluate short-term clinical and radiographic outcomes of this novel implant.
- Assess feasibility in patients with idiopathic talar necrosis.
Main Methods:
- Prospective clinical trial under rare-disease framework.
- Six patients underwent total talar arthroplasty with 3D-printed implants.
- Interim analysis of three patients with 6-week and 3-month follow-up.
Main Results:
- Mean follow-up of 16 weeks.
- Visual analog scale (VAS) pain scores decreased significantly.
- Foot and Ankle Outcome Score (FAOS) improved, particularly in pain and daily living.
- Ankle range of motion (ROM) generally maintained or improved.
Conclusions:
- Total talar replacement with patient-specific implants shows promise for preserving joint function.
- Early clinical outcomes suggest improved pain and function in advanced talar AVN.
- Further follow-up is necessary to confirm long-term safety and durability.

