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FNDC5 and ACOX1 as Biomarkers of Peroxisomal Activity with Contrast Outcomes in Colon Adenocarcinoma

Yuan Hepei1, Zeng Jun2, Khan Muhammad1

  • 1Department of Radiation Oncology, Guangzhou Institute of Cancer Research, the Affiliated Cancer Hospital, Guangzhou Medical University, No. 78 Hengzhigang Road, Yuexiu District, Guangzhou, Guangdong, 510095, People's Republic of China.

Biological Procedures Online
|July 23, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Colorectal Cancer (CRC)Fatty Acid MetabolismFibroblastsPeroxisomesTumor Microenvironment (TME)

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Peroxisomes are specialized organelles present in fungi, plant, and animal cells. It can vary in number, size, morphology, and activity depending on the type of tissue and the nutritional state of the cell. For example, cells with active lipid metabolism, such as adipocytes, neurons, and hepatocytes, have more peroxisomes than other cells in the body. Besides their primary role in breaking down complex organic molecules, peroxisomes can also synthesize specific macromolecules and participate in...
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