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Primary Hyperaldosteronism Presenting as Cardiac Arrest: A Case Report

Maryam Saleem1,2,3, Maahin M Khan4, Hassaan Iftikhar1,2,5

  • 1Nephrology, Ohio Valley Nephrology Associates, Owensboro, USA.

Cureus
|July 24, 2025
PubMed

Insights

Primary hyperaldosteronism, a common hypertension cause, can lead to severe hypokalemia and cardiac arrest. Early diagnosis and treatment, like adrenalectomy, are crucial for patient outcomes.

Area of Science:

  • Endocrinology
  • Cardiology
  • Nephrology

Background:

  • Primary hyperaldosteronism is an underdiagnosed cause of hypertension, linked to increased cardiovascular risks.
  • It often presents as treatment-resistant hypertension and hypokalemia.

Observation:

  • A patient experienced cardiac arrest due to severe hypokalemia.
  • This critical event prompted further investigation into underlying causes.

Findings:

  • The patient was diagnosed with primary hyperaldosteronism.
  • Diagnosis was confirmed using adrenal vein sampling.
  • Successful treatment involved a left adrenalectomy.

Implications:

  • Highlights the critical need for early recognition of primary hyperaldosteronism.
  • Emphasizes the severe cardiovascular consequences of undiagnosed hyperaldosteronism.
  • Demonstrates the efficacy of surgical intervention for primary hyperaldosteronism.

Keywords:
adrenal adenomacardiac arresthypokalemiaprimary hyperaldosteronismresistant hypertensionsecondary hypertension

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