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Coronavirus in Recent Years: Characteristics, Outbreaks, and Treatments
Touba Eslaminejad1, Saeedeh Shojaeepour2, Seyedeh Atekeh Torabizadeh3,4
1Department of Anatomy, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Tanaffos
|July 24, 2025
Summary
Elderly males with diabetes or heart disease face higher risks from coronaviruses like COVID-19. Early diagnosis and combination therapy improve outcomes for these severe respiratory illnesses.
Area of Science:
- Medical Research
- Infectious Diseases
- Public Health
Background:
- Coronaviruses cause severe acute respiratory syndromes, including SARS, MERS, and COVID-19.
- Treatment effectiveness is influenced by patient age, diagnostic timeliness, and hospitalization duration.
- Understanding these influencing factors is crucial for managing coronavirus infections.
Purpose of the Study:
- To investigate the interplay between patient demographics, medical history, and treatment outcomes in severe respiratory syndromes.
- To analyze the impact of diagnostic methods and therapeutic strategies on coronavirus patient recovery.
Main Methods:
- A systematic literature search was conducted across five major databases (MEDLINE, EMBASE, WOS, Science Direct, Cochrane Library) from 2010-2024.
- Fifty-five original case reports focusing on signs and treatments of coronavirus infections were selected and analyzed.
- Data extraction included patient age, gender, medical history, diagnostic methods, treatments, syndrome type, and transmission routes.
Main Results:
- Severe respiratory syndromes disproportionately affected the elderly and males (58% vs. 42%).
- Pre-existing conditions like diabetes and heart disease significantly increased severity.
- Clinical diagnostic methods were favored for efficiency; combination therapy outperformed single-drug treatments.
- Human-to-human and nosocomial transmission were the most common routes.
Conclusions:
- Effective management of fatal respiratory illnesses hinges on healthcare providers' familiarity with specific pathogens.
- Early and appropriate treatment strategies are paramount for controlling coronavirus outbreaks and improving patient survival rates.
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