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The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
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Related Experiment Video

Updated: Sep 14, 2025

Objectification of Tongue Diagnosis in Traditional Medicine, Data Analysis, and Study Application
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A Weighted Voting Approach for Traditional Chinese Medicine Formula Classification Using Large Language Models:

Zhe Wang1,2, Keqian Li3, Suyuan Peng4

  • 1Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences; School of Basic Medicine, Peking Union Medical College, Beijing, China.

JMIR Medical Informatics
|July 24, 2025
PubMed
Summary
This summary is machine-generated.

This study shows that ensemble learning with large language models (LLMs) significantly improves traditional Chinese medicine (TCM) formula classification accuracy. The best ensemble model achieved 77.15% accuracy, enhancing TCM knowledge discovery.

Keywords:
TCM formula classificationalgorithm developmentensemble learninglarge language modelstraditional Chinese medicine

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Area of Science:

  • Biomedical Informatics
  • Computational Linguistics
  • Traditional Chinese Medicine

Background:

  • Traditional Chinese Medicine (TCM) formulas possess critical information on ingredients, efficacy, and indications.
  • Classifying TCM formulas is essential for standardization, clinical support, research, and modernization.
  • Large Language Models (LLMs) offer advanced capabilities for enhancing TCM knowledge discovery.

Purpose of the Study:

  • To evaluate the performance of various LLMs in classifying TCM formulas.
  • To improve TCM formula classification accuracy using ensemble learning with fine-tuned LLMs.

Main Methods:

  • Manually curated and cleaned dataset of 2441 TCM formulas.
  • Fine-tuned 10 Chinese-supporting LLMs.
  • Employed ensemble learning with hard and weighted voting mechanisms.
  • Selected top-performing models for ensemble voting (top 5 and top 3).

Main Results:

  • Qwen-14B achieved the highest single-model accuracy at 75.32%.
  • Ensemble methods improved accuracy: hard voting (75.79%), weighted voting (76.47%), weighted voting (top 5) (75.57%), and weighted voting (top 3) (77.15%).

Conclusions:

  • Ensemble learning with LLMs effectively enhances TCM formula classification accuracy.
  • The proposed method improves the classification system for TCM formula efficacy.
  • This approach accelerates TCM knowledge discovery and promotes scientific application.