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Updated: Sep 14, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Catheter ablation as first line therapy for atrial fibrillation
Maham F Karatela1, Hugh Calkins1
1Johns Hopkins Hospital, Department of Cardiology, United States of America.
None:
The treatment for atrial fibrillation has evolved significantly over time. Previously, medication management was the mainstay of treatment. As we have developed more robust technologies and modalities for catheter ablation, these treatment recommendations have changed. Catheter ablation is a safe and effective strategy for treating atrial fibrillation that is now considered first-line therapy in some patient populations. In this review, we discuss historical perspectives regarding the treatment and management of atrial fibrillation. We review the literature on studies investigating catheter ablation as first-line therapy, including the impact of catheter ablation on arrhythmia recurrence, cardiovascular outcomes, and healthcare utilization. Finally, we discuss future directions for the management of atrial fibrillation as the technology for catheter ablation continues to grow and progress.
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