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Post-transplant Lymphoproliferative Disorder Successfully Treated with Pola-R-CHP and Achieved Long-term Remission
Masahiro Shino1, Akira Honda1, Hideaki Mizuno1
1Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Japan.
Abstract:
Post-transplant lymphoproliferative disorder (PTLD) is a life-threatening condition for organ transplantations. There are no established treatments for PTLD, and it is associated with a poor prognosis. Patients with PTLD treated with Pola-R-CHP have rarely been reported, and long-term remission results are unknown. This is the first report of previously untreated PTLD treated with a Pola-R-CHP regimen that achieved long-term remission. Pola-R-CHP may be a promising treatment option for patients with PTLD, especially monomorphic diffuse large B-cell lymphoma, and those with an increased International Prognostic Index score.

