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Updated: May 12, 2026

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
Published on: June 7, 2015
Smart hydrogels for in situ tissue drug delivery
1Institute of Polymer Science and Engineering, National Taiwan University, No. 1, Sec. 4 Roosevelt Road, Taipei, 106319, Taiwan, ROC.
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The application of smart hydrogels has become a booming research frontier in biomedical engineering. With the development of intelligent drug delivery systems, various biomimetic and biodegradable hydrogels are employed for localized drug delivery to tissues in the preclinical applications. These advanced materials are designed to match the diverse environmental and functional requirements of various tissue types and organs. This article discusses the attractive characteristics of smart hydrogels as delivery systems and reviews the design of a range of smart hydrogels, as well as the challenges of tissue-specific drug delivery, focusing on the last 5 years of frontward research.
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