Related Experiment Video
Updated: Sep 14, 2025

Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research
Published on: October 22, 2014
Firefighters Versus Law Enforcement Officers: A Comparison of Cardiovascular Disease Risk
Bethany C Guerra1, Steven E Martin1,2, Lisa C Colvin1
1Tactical Athlete Research Unit, Department of Kinesiology and Sports Management, Texas A&M University, College Station, TX, USA.
Abstract:
Firefighters (FFs) and law enforcement officers (LEOs) have heightened cardiovascular disease (CVD), with data suggesting that ≈45% of on-duty FF fatalities are related to CVD, while LEOs have a 1.7 times higher CVD prevalence than the general public. This study compared CVD risk biomarkers, fitness, and body composition between FFs and LEOs. Ninety-eight career, structural male FFs (age = 35.1±9.6 yrs; weight = 94.3±15.4 kg; height = 178.4±13.2 cm) and seventy-three career LEOs (age = 41.4±9.0 yrs; weight = 92.3±16.8 kg; height = 179.6±8.1 cm) from local departments were studied. Participants completed a maximal cardiopulmonary exercise test (CPXT), where VO2max was estimated from the Foster equation. Fasted blood was collected to assess CVD risk biomarkers. Dual-energy X-ray absorptiometry assessed body composition, and waist and hip measures were taken. Analyses with and without women participants were conducted to assess differences in CVD risk biomarkers, fitness, and body composition between the FFs and LEOs. Effect sizes were calculated and reported as Cohen's d. Univariate general linear model (GLM) analysis of covariance (ANCOVA) were conducted to account for age as a covariate, wherein partial Eta squared (ηp 2) values were used to assess effect size for the GLM statistics. FFs had higher (p<0.05) CPXT exercise times (FFs: 10.9±1.6 min; LEOs: 10.3±2.0 min; d=0.366) compared to LEOs. FFs also had higher (p<0.05) advanced oxidation protein products (FFs: 134.8±90.1 μM; LEOs: 106.8±67.6 μM; d=0.342), blood cortisol (FFs: 14.2±5.0 μg/dL; LEOs: 12.5±5.6 μg/dL; d=0.325), and waist-to-hip ratios (FF: 0.95±0.06; LEO: 0.89±0.08; d=0.792). These findings suggest that while FFs demonstrated greater CPXT time-to-exhaustion, they also expressed higher stress and CVD risk biomarkers concentrations than LEOs. These data suggest that occupation-specific characteristics and stressors may play a role in the CVD risk profile of first responders.
More Related Videos
10:11Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies
Published on: October 22, 2014
07:20Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
Published on: January 28, 2014
Related Concept Videos
Relative Risk
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Coronary Artery Disease I: Introduction
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
Assessment of the Cardiovascular System I: Subjective Data
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...