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Related Experiment Video

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X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging
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Feasibility Study of Dose Reduction in Digital Breast Tomosynthesis Using Non-Local Denoising Algorithms.

Marcelo A C Vieira1, Helder C R de Oliveira1, Polyana F Nunes1

  • 1Department of Electrical Engineering, University of São Paulo, São Carlos, SP, Brazil.

Proceedings of Spie--The International Society for Optical Engineering
|July 25, 2025
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Summary

This study shows that denoising algorithms can reduce radiation dose in Digital Breast Tomosynthesis (DBT) imaging. The Block-matching 3D (BM3D) algorithm effectively reduces noise and preserves image quality at lower doses.

Keywords:
Digital breast tomosynthesisblock-matching 3Ddose reductionimage denoisingnon-local means

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Area of Science:

  • Medical Imaging
  • Radiology
  • Image Processing

Background:

  • Digital Breast Tomosynthesis (DBT) involves higher radiation doses than standard mammography due to "combo-mode" imaging.
  • Reducing radiation dose in DBT is crucial for patient safety, but it increases quantum noise and degrades image quality.

Purpose of the Study:

  • To evaluate the effectiveness of denoising algorithms in reducing radiation dose for DBT examinations.
  • To assess if denoising techniques can maintain acceptable image quality despite dose reduction.

Main Methods:

  • Two "state of the art" denoising techniques, Non-local Means (NLM) and Block-matching 3D (BM3D), were investigated.
  • DBT projections were acquired from a breast phantom at various radiation dose levels.
  • Optimal filtering parameters were determined to recover image quality.

Main Results:

  • BM3D demonstrated superior noise reduction and less image blurring compared to NLM.
  • BM3D achieved better noise adjustment (mean difference in peak signal to noise ratio < 0.1dB).
  • BM3D resulted in less image blurring (mean difference in image sharpness ~ 6%).

Conclusions:

  • Denoising algorithms, particularly BM3D, show significant potential for reducing radiation dose in DBT.
  • BM3D effectively mitigates noise and preserves image quality in low-dose DBT projections.
  • These findings support the clinical implementation of dose reduction strategies in DBT imaging.