[Endoscopic Management of Ampulla of Vater Tumors]

The management of tumors of the ampulla of Vater ranges from palliative care to endoscopic papillectomy and surgical resection. Treatment decisions should be based on a comprehensive assessment of multiple factors, including the lesion characteristics (e.g., size, location, and evidence of malignancy), the patient's overall health status, individual preferences, and the availability of local expertise. When an endoscopic papillectomy is selected as the treatment modality, it must be performed by an experienced endoscopist, with careful patient selection and strict adherence to the established indications. The indications for endoscopic papillectomy may broaden with ongoing advances in endoscopic techniques and diagnostic imaging. Nevertheless, patient safety must remain the foremost concern, with the goal of achieving complete and safe tumor resection while minimizing morbidity and mortality.