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Real World Case Series: A.G.E. Interrupter Ultra Serum.
Sonya Abdulla1, Patricia Brieva2, Hugues Cartier3
1Dermatology on Bloor, Toronto, Ontario, Canada.
Journal of Cosmetic Dermatology
|July 25, 2025
Summary
This study shows that A.G.E. Interrupter serum, when used with collagen-stimulating procedures, improves skin aging signs. Dermatologists observed enhanced results and high patient satisfaction in a diverse patient group.
Area of Science:
- Dermatology and cosmetic science.
- Skin aging and rejuvenation research.
Background:
- A.G.E. Interrupter serum formulation includes proxylane, Cassia alata, and botanical extracts.
- Ex vivo studies demonstrate the serum's potential to upregulate key dermal-epidermal junction (DEJ) components like collagen IV and laminin.
- The serum aims to counteract DEJ degradation, a factor in skin weakening and structural decline.
Purpose of the Study:
- To present a case series on A.G.E. Interrupter serum as an adjunct to collagen-stimulating procedures.
- To evaluate its efficacy across diverse patient demographics and skin types.
Main Methods:
- An expert panel of eight dermatologists was convened.
- Dermatologists shared anonymized patient cases (2 each) utilizing the serum with collagen-stimulating treatments.
Main Results:
- Seven patient cases were selected for analysis, showcasing integrated skincare regimens.
- Daily post-procedure application of the serum reportedly enhanced overall outcomes.
- High levels of patient satisfaction were noted with the combined treatment approach.
Conclusions:
- This case series supports the use of A.G.E. Interrupter serum within varied skincare protocols.
- The findings suggest the serum's utility in optimizing results for patients undergoing rejuvenation procedures.

